张江江，助理教授/特别副研究员，硕士生导师

邮箱：zhangjj@bit.edu.cn；北京理工大学中关村校区5号楼724

欢迎具有化学、材料、生物化学与分子生物学等专业背景的同学加入！

教育与科研工作经历

2022.12-至今  北京理工大学生命学院，助理教授/特别副研究员，硕士生导师

2019.7-2022.11  南方科技大学/东南大学，博士后，合作导师：蒋兴宇/赵远锦教授

2015.9-2018.12  国家纳米科学中心，化学：纳米科学与技术，博士，导师：蒋兴宇研究员

2012.9-2015.7 上海大学生命科学学院，生物化学与分子生物学，硕士，导师：李根喜教授

研究方向

1、纳米材料表面化学分析与修饰（表界面调控）

2、功能性纳米材料/纳米酶

3、新型荧光MOF/COF/HOF纳米材料

4、水凝胶、薄膜智能生化传感器

5、可视化分析检测/体外诊断/POCT/单分子免疫检测

6、AIE型功能荧光分子探针设计合成与应用

科研项目

1、北京理工大学“青年教师学术启动计划”，2023 - 2025，40万，在研，主持

2、国家自然科学基金重点项目,器官共形适配的生物检测系统,2023 - 2027,280万元,在研,参与

3、国家自然科学基金青年科学基金项目,荧光MOF@Au Janus颗粒设计合成及其在试纸条增强检测上的应用研究,2022 - 2024,30万元,在研,主持

4、国家重点研发计划“生物与信息融合”重点专项，可调控光感智能生物眼的开发与设计-课题四子项目，2022 - 2025，66.7万元，在研，主持

5、深圳市科创委面上项目,可视化检测新型冠状病毒/甲型/乙型流感病毒核酸生物传感器的研究,2021 - 2024,40万元,在研,参与

6、国家自然科学基金重点项目,利用微流控/纳米技术构建血管/神经网络用于再生医学,2018 - 2022,290万元,已结题,参与

代表性论文

(1)        Jiangjiang Zhang*, Fengli Chai, Jia’an Li, Saijie Wang, Shuailong Zhang, Fenggang Li, Axin Liang, Aiqin Luo, Dou Wang*, Xingyu Jiang*; Weakly ionized gold nanoparticles amplify immunoassays for ultrasensitive point-of-care sensors, Science Advances 2024, 10, eadn5698.

(2)        Jiangjiang Zhang^#, Ying Li^#, Fengli Chai^#, Qizhen Li, Dou Wang, Liping Liu*, Ben Zhong Tang*, Xingyu Jiang*; Ultrasensitive point-of-care biochemical sensor based on metal-AIEgen frameworks, Science Advances 2022, 8, eabo1874.

(3)        Xirui Chen, Qi Liu, Jiangjiang Zhang*, Linjie Tan, Jiangao Li, Miao-La Ke*, Ben Zhong Tang*, Ying Li*; Fully Inter-restricted Assembly of Aggregation-Induced Emission Luminogens and Polymers Enables Ultra-bright Nanoparticles for Sensitive Point-of-Care Diagnosis, ACS Nano 2025, 19, 6221-6235

(4)        Fengli Chai, Dou Wang, Fei Shi, Wenfu Zheng, Xiaohui Zhao, Yao Chen, Cuiping Mao, Jiangjiang Zhang*, Xingyu Jiang*; Dual Functional Ultrasensitive Point-of-Care Clinical Diagnosis Using Metal–Organic Frameworks-Based Immunobeads, Nano Letters 2023, 23, 9056-9064

(5)        Mian Chen^#, Jiangjiang Zhang^#, Jie Qi, Ruihua Dong, Hongmei Liu, Decheng Wu, Huawu Shao*, Xingyu Jiang*; Boronic acid-decorated multivariate photosensitive metal–organic frameworks for combating multi-drug-resistant bacteria, ACS Nano 2022, 16, 7732-7744.

(6)        Jiangjiang Zhang, Zhentao Huang, Yangzhouyun Xie, Xingyu Jiang*; Modulating the catalytic activity of gold nanoparticles using amine-terminated ligands, Chemical Science 2022, 13, 1080-1087.

(7)        Jiangjiang Zhang, Yuexiao Jia, Jie Qi, Weixiao Yan, Xingyu Jiang*; Four-in-one: Advanced copper nanocomposites for multianalyte assays and multicoding logic gates, ACS Nano 2020, 14, 9107-9116.

(8)        Rui Chen, Yongzhen Dong, Shuhuai Li, Xionghui Ma, Chaohai Pang, Shu Wang, Jiangjiang Zhang*, Yiping Chen*; A particle counting immunosensor for the sensitive detection of ochratoxin A via click chemistry-mediated signal amplification, Journal of Hazardous Materials 2025, 488, 137381

(9)        Ruilin Haotian, Ziyu Zhu, Heao Zhang, Tianjian Lv, Shanshan Tang, Jiangjiang Zhang*, Aiqin Luo*, Axin Liang*; Engineering conductive covalent-organic frameworks enable highly sensitive and anti-interference molecularly imprinted electrochemical biosensor, Biosensors & Bioelectronics 2025, 273, 117195

(10) Axin Liang, Tianjian Lv, Bingchen Pan, Ziyu Zhu, Ruilin Haotian, Yao Xie, Liquan Sun, Jiangjiang Zhang*, Aiqin Luo*; Dynamic simulation and experimental studies of molecularly imprinted label-free sensor for determination of milk quality marker, Food Chemistry 2024, 449, 139238

(11)     Aoting Gu, Yongzhen Dong, Letian Li, Deyang Yu, Jiangjiang Zhang*, Yiping Chen*; CRISPR/Cas12a and Hybridization Chain Reaction-Coregulated Magnetic Relaxation Switching Biosensor for Sensitive Detection of Viable Salmonella in Animal-Derived Foods, Journal of Agricultural and Food Chemistry 2024, 72, 20130-20139

(12)     Jincheng Xiong, Boyan Sun, Shuai Zhang, Linqian Qin, Jiangjiang Zhang*, Haiyang Jiang*; A novel one-step immunoassay using mesoporous core-shell Pd@Pt nanoparticles as an alternative to horseradish peroxidase for amantadine detection, Talanta 2025, 291, 127898

(13)     Jiangjiang Zhang^#, Lei Mou^#, Xingyu Jiang*; Surface chemistry of gold nanoparticles for health-related applications, Chemical Science 2020, 11, 923-936.

(14)     Jiangjiang Zhang, Wenshu Zheng, Xingyu Jiang*; Ag⁺-gated surface chemistry of gold nanoparticles and colorimetric detection of acetylcholinesterase, Small 2018, 14, 1801680.

(15)     Jiangjiang Zhang, Lei Mou, Xingyu Jiang*; Hydrogels incorporating Au@polydopamine nanoparticles: Robust performance for optical sensing, Analytical Chemistry 2018, 90, 11423 -11430.

(16) Yangyang Chen^#, Jiangjiang Zhang^#, Yanmin Gao, Jaebeom Lee, Hongxia Chen*, Yongmei Yin*; Visual determination of aliphatic diamines based on host–guest recognition of calix[4]arene derivatives capped gold nanoparticles, Biosensors and Bioelectronics 2015, 72, 306-312.

(17) Hongxia Chen^#, Jiangjiang Zhang^#, Yanmin Gao, Siyu Liu, Kwangnak Koh, Xiaoli Zhu*, Yongmei Yin*; Sensitive cell apoptosis assay based on caspase-3 activity detection with graphene oxide-assisted electrochemical signal amplification, Biosensors and Bioelectronics 2015, 68, 777-782.