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生物医学工程系

生物医学工程系教师简介 —— 闫天翼 教授 / 博士生导师

来源:    编辑:肖雯   审核:周连景   发布日期:2021-04-12

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闫天翼

北京理工大学教授、博士生导师

生命学院副院长,生物医学工程系主任,

国家高层次青年人才、北京市科技新星

邮箱:yantianyi@bit.edu.cn      电话:15210108910


教育经历

· 2007/04-2011/10,Okayama University,Biomedical Engineering,Okayama,Japan. PhD/Postdoc

· 2004/09-2007/03,Kagawa University,Intelligent Systems,Kagawa,Japan,M.S.

· 2000/09-2004/09,Chang Chun University of Science and Technology,Electronic and Information Engineering,B.S.

工作经历

· 2020/03-现在,  北京理工大学,生命学院,副院长

· 2018/07-现在,  北京理工大学,生命学院,生物医学工程系  主任

· 2016/07-现在,  北京理工大学,生命学院,教授  博士生导师

· 2012/07-2016/06,北京理工大学,生命学院,副教授

· 2011/10-2012/06,北京理工大学,生命学院,讲师

研究方向

· 脑科学,类脑计算

  多感觉脑功能图谱;工作记忆

· 多模态医学影像数据解码、编码模型

  脑电、功能磁共振信号解析;复杂脑网络算法;机器学习算法

· 脑神经疾病早期诊断、康复机制与仪器设备开发

  神经精神类疾病早期诊断;神经调控康复技术

获得奖项

· 中国发明协会  发明创新奖  一等奖  2021.10

· 北京理工大学 教学成果一等奖 2021.7

· Trainee Abstract Travel Award. OHBM 2012, 18th Annual Meeting of the Organization for Human Brain Mapping

· Best Poster Paper Award, 2015 ICME International Conference on Complex Medical Engineering, IEEE/CME 2015, June 2015

· Best Poster Paper Award, 2th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics, CISP-BMEI 2009, October 2009

主持科研项目

1. 中华人民共和国科学技术部,国家重点研发计划,2018YFC0115400,闭环生物反馈和无创深 部电刺激调控协同系统研发与帕金森病治疗应用研究,2018-2021,主持;

2. 国家自然科学基金委员会联合基金,重点项目,U20A20191,基于柔性微针传感的生理与运动信息融合模型及在帕金森病个体化康复中的应用研究,2021-2024,主持;

3. 国家自然科学基金委员会,面上项目,81671776,基于立体宽视野脑功能成像技术的跨通道情绪识别脑机制研究,2017-01 至2020-12,主持;

4. 北京市科学技术委员会,北京市科技专项,Z201100007720009,基于精准电刺激调控技 术的脑功能增强研究,2020 - 2022,主持;

5. 北京市科学技术委员会,北京市科技专项,Z181100003118007,面向生物-机器人的人工神经接口关键技术研究,2018-2020,主持;

6. 第五批青年拔尖人才支持计划,脑机智能与神经调控,2020- 2022,主持;

7. 教育部博士学科点优秀青年教师基金,20121101120042,基于宽视野脑功能成像的恐惧与厌恶面部表情识别的脑机制研究,2012/01-2014/12,主持;

8. 国家自然科学基金青年基金,61305142,基于宽视野脑功能成像技术的视觉空间面部表情识别的脑机制研究,2014/01-2016/12,主持;

9. 北京市科学技术委员会,脑认知与脑医学专项,Z161100002616020,脑认知与脑医学-基于神经反馈训练的可穿戴阿尔茨海默病干预系统研究,2016-2019,主持;

10. 北京市科学技术委员会,科技新星与领军人才培养,Z171100001117057,科技新星-闫天翼2017- 2019,主持;

11. 国家自然科学基金委员会,重点项目,61633018,基于神经影像技术的认知下降预测及其在AD 临床前期诊疗中的应用,2017- 2021,参与;

12. 国家自然科学基金委员会,国家重大科研仪器研制项目,61727807,触觉感知脑功能拓扑图测量仪,2018-2022,参与;

13. 中华人民共和国科学技术部,国家重点研发计划子课题,2017YFB1002504,基于虚拟现实的混合脑机交互关键技术与装置,2017-2021,骨干;

近5年科研论文选篇 (*: 通讯作者)

1. Liu T, Wang L, Suo D, Zhang J, Wang K, Wang J, Chen D, Yan T*. Resting-state functional MRI of healthy adults: temporal dynamic brain co-activation patterns. Radiology. 2022.03. 2022 May 3;211762. (中科院TOP,IF: 11.10)

2. Yan T; Wang G, Wang L, Liu T, Li T, Wang L, Chen D, Funahashi S, Wu, J. Wang B*, Suo, D*. Episodic Memory in Aspects of Brain Information Transfer by Resting-State Network Topology, Cerebral Cortex, 2022.02. DOI10.1093/cercor/bhab526. (中科院TOP,IF: 6.108)

3. Wang L, Li C*, Han Z, Wu Q, Sun L, Zhang X, Go R, Wu J, Yan T* ; Spatiotemporal and sensory modality attention processing with domain-specific representations in frontoparietal areas, Cerebral Cortex, 2022, bhac029: 1-14. (中科院TOP,IF: 6.108)

4. D. Wang, B.Wu, G.Zhao, M. Yao, H. Chen, L. Deng, Yan T* and G. Li*, Kronecker CP Decomposition with Fast Multiplication for Compressing RNNs, IEEE Transactions on Neural Networks and Learning Systems,2021.09. DOI10.1109/TNNLS.2021.3105961 (中科院TOP,IF: 11.68)

5. Chen D*, Zhang X, Mei Y, Liao F, Xu H, Li Z, Xiao Q, Guo W, Zhang H, Yan T*, Xiong J*, Ventikos Y. Multi-stage learning for segmentation of aortic dissections using a prior aortic anatomy simplification. Med Image Anal. 2021 Apr;69:101931. (中科院TOP,IF: 11.148)

6. Wang L, Zhang Z, Okada T, Li C, Chen D, Funahashi S, Wu J, Yan T*. Population receptive field characteristics in the between and within-digit dimensions of the undominant hand in the primary somatosensory cortex. Cerebral Cortex, 2021;00: 1–12 (中科院TOP,IF: 6.108)

7. Wang H, Sun W, Zhang J, Yan Z, Wang C, Wang L, Liu T, Li C, Chen D, Shintaro F, Wu J, Yan T*.Influence of layered skull modeling on the frequency sensitivity and target accuracy in simulations of transcranial current stimulation, Human Brain Mapping, 2021,1:12. (中科院TOP,IF: 5.038)

8. Wang L, Li C, Chen D, Lv X, Go R, Wu J, Yan T*. Hemodynamic response varies across tactile stimuli with different temporal structures. Human Brain Mapping. 2021 Feb 15;42(3):587-597. doi: 10.1002/hbm.25243. Epub 2020 Nov 10. (中科院TOP,IF: 5.038)

9. Liu T, Yan Y, Ai J, Chen D, Wu J, Fang B*, Yan T*. Disrupted rich-club organization of brain structural networks in Parkinson's disease [J]. Brain structure & function, 2021, 226(7): 2205-17. (中科院TOP,IF: 3.587)

10. Yan T, Liu T, Ai J, Shi Z, Zhang J, Pei G*, Wu J. Task-induced activation transmitted by structural connectivity is associated with behavioral performance. Brain Struct Funct. 2021 Mar 20. doi: 10.1007/s00429-021-02249-0. (中科院TOP,IF: 3.587)

11. Song D#, Wang D#, Yang Q#, Yan T#, Wang Z, Yan Y, Zhao J, Xie Z, Liu Y, Ke Z, Talal J, Li Y, Wu Y, Shi Q, Lang Y, Zhang H, Huang T, Wang C, Quan Z*, Qing H*. The lateralization of left hippocampal CA3 during the retrieval of spatial working memory. Nature Communications, 2020, 11(1):2901. (中科院TOP,IF: 12.121)

12. Zhang WR, Wang K, Yin L, Zhao WF, Xue Q, Peng M, Min BQ, Tian Q, Leng HX, Du JL, Chang H, Yang Y, Li W, Shangguan FF, Yan T, Mental Health and Psychosocial Problems of Medical Health Workers during the COVID-19 Epidemic in China. Dong HQ, Han Y, Wang YP, Cosci F, Wang HX. Psychother Psychosom. 2020;89(4):242-250. Epub 2020 Apr 9. (中科院TOP,IF: 19.009热点论文,高被引)

13. Yan T*, Wang W,Yang L, Chen K, Chen R, and Han Y. Rich club disturbances of the human connectome from subjective cognitive decline to Alzheimer’s disease, Theranostics 2018, Vol. 8, Issue 12. (中科院TOP,IF: 11.629)

14. Wang H, Wang L, Zhang W, Xue Q, Peng M, Sun Z, Li L, Wang K, Yang X, Jia Y, Zhou Q, Xu Z, Li N, Dong K, Zhang Q, Song H, Zhan S, Min B, Fan C, Zhou A, Guo X, Li H, Liang L, Yin L, Si TM, Huang J, Yan T, Cosci F, Kamiya A, Lu J, Wang Y. Effect of Transcranial Alternating Current Stimulation for the Treatment of Chronic Insomnia: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Clinical Trial. Psychother Psychosom. 2020;89(1):38-47. (中科院TOP,IF: 19.009)

15. Chen D*, Wei J, Deng Y, Xu H, Li Z, Meng H, Han X, Wang Y, Wan J, Yan T*, Xiong J*, Tang X. Virtual stenting with simplex mesh and mechanical contact analysis for real-time planning of thoracic endovascular aortic repair. Theranostics. 2018 Nov 10;8(20):5758-5771. doi: 10.7150/thno.28944. (中科院TOP,IF: 11.629)

16. Deng Y, Chen D, Wang L, Gao F, Jin B, Lv H, Zhang G, Sun X, Liu L, Mo D, Ma N, Song L, Huo X, Yan T*, Miao Z*. Silencing of Long Noncoding RNA Nespas Aggravates Microglial Cell Death and Neuroinflammation in Ischemic Stroke. Stroke. 2019 Jul;50(7):1850-1858. (中科院TOP,IF: 8.032)

17. Wu J#, Yan T#, Zhang Z, Jin F, Guo Q. Retinotopic mapping of the peripheral visual field to human visual cortex by functional magnetic resonance imaging. Hum Brain Mapp. 2012 Jul;33(7):1727-40. (中科院TOP,IF: 5.038).

18. Zhang D, Liu S, Wang K, Zhang J, Chen D, Zhang L, Nie L, Yang J, Shinntarou F, Wu J, Yan T*. Machine-vision fused brain machine interface based on dynamic augmented reality visual stimulation. J Neural Eng. 2021 Oct 19;18(5). doi: 10.1088/1741-2552/ac2c9e.

19. Yang Y#, Deng L#, Wu S, Yan T*, Xie Y, Li G*. T, Training high-performance and large-scale deep neural networks with full 8-bit integers. Neural Networks, 2020, 125:70-82.

20. Pei G, Yang R, Shi Z, Guo G, Wang S, Liu M*, Qiu Y, Wu J, Go R, Han Y*, Yan T*. Enhancing Working Memory Based on Mismatch Negativity Neurofeedback in Subjective Cognitive Decline Patients: A Preliminary Study [J]. Frontiers in aging neuroscience, 2020, 12: 12.

21. Li T#, Wang B#, Gao Y, Wang Xin, Yan Ting, Xiang J, Niu Y, Liu T, Chen D, Fang B, Xie Y, Funahashi S, Yan T*. APOE epsilon 4 and cognitive reserve effects on the functional network in the Alzheimer's disease spectrum [J]. Brain imaging and behavior, 2021, 15(2): 758-71.

22. Wang L#, Zhang J#, Liu T, Chen D, Go R, Wu J, Yan T*. Prediction of cognitive task activations via resting-state functional connectivity networks: an EEG Study. IEEE Transactions on Cognitive and Developmental Systems, 2020, PP(99):1-1.

23. Chen H, Deng L, Qu Z, Liang L, Yan T, Xie Y, Li G. Tensor train decomposition for solving large-scale linear equations. Neurocomputing 464 (2021) 203–217

24. Wang L#, Wang W#, Yan T*, Song J, Yang W, Wang B, Go R, Huang Q, Wu J*. Beta-band functional connectivity influences audiovisual integration in older age: an EEG study. Frontiers in Aging Neuroscience, 2017, 9: 239.

25. Jia S, Wang L, Wang H, Lv X, Wu J, Yan T*, Hu B. Pneumatical‐mechanical tactile stimulation device for somatotopic mapping of body surface during fMRI. Journal of Magnetic Resonance Imaging, 2020, May.

26. Yang L#, Yan Y#, Li Y, Hu X, Lu J, Chan P, Yan T*, Han Y*. Frequency-dependent changes in fractional amplitude of low-frequency oscillations in Alzheimer's disease: a resting-state fMRI study. Brain Imaging Behav. 2020 Dec;14(6):2187-2201.

27. Bai Z#, Chen D#, Wang L, Zhao Y, Liu T, Yun Yu, Yan T*, Cheng Y*. Cerebrospinal Fluid and blood cytokines as biomarkers for multiple sclerosis: a systematic review and meta-analysis of 226 studies with 13526 MS patients.” Frontiers in Neuroscience, 2019, 13: 1026.

28. Yang L, Yan Y, Wang Y, Hu X, Lu J, Chan P, Yan T*, Han Y*. Gradual Disturbances of the Amplitude of Low-Frequency Fluctuations (ALFF) and Fractional ALFF in Alzheimer Spectrum. Front Neurosci. 2018 Dec 20;12:975. doi: 10.3389/fnins.2018.00975.

29. Xie Y, Liu T, Ai J, Chen D, Zhuo Y, Zhao G, He S, Wu J, Han Y, Yan T*. Changes in Centrality Frequency of the Default Mode Network in Individuals With Subjective Cognitive Decline. Front Aging Neurosci. 2019 Jun 20;11:118. doi: 10.3389/fnagi.2019.00118.

30. BrainKilter: A Real-Time EEG Analysis Platform for Neurofeedback Design and Training. Pei G, Guo G, Chen D, Yang R, Shi Z, Wang S, Zhang J, Wu J, Yan, Yan T*. IEEE Access, v 8, p 57661-57673, 2020

31. Yan T*, Wang Y, Weng Z, Du W, Liu T, Chen D, Li X, Wu J, Han Y*. Early-Stage Identification and Pathological Development of Alzheimer's Disease Using Multimodal MRI. J Alzheimers Dis. 2019;68(3):1013-1027. doi: 10.3233/JAD-181049

32. Zhang Z, Guo G, Zhang J, Li C, Huang Q, Go R, Fukuyama H, Funahashi S, Yan T*, Wu J. Do theta oscillations explain the somatosensory change detection mechanism? Biol Psychol. 2019 Apr;143:103-112. doi: 10.1016/j.biopsycho.2019.02.001. Epub 2019 Feb 13.

33. Deng YM, Chen DD, Wang LY, Gao F, Sun X, Liu L, Lei K, Wang SR, Mo DP, Ma N, Song LG,Huo XC, Xu XT, Yan T*, Miao ZR*. Visual field impairment predicts recurrent stroke after acute posterior circulation stroke and transient ischemic attack. CNS Neurosci Ther. 2018 Feb;24(2):154-161. doi: 10.1111/cns.12787.

34. Yang L, Yan Y, Wang Y, Hu X, Lu J, Chan P, Yan T*, Han Y*. Gradual Disturbances of the Amplitude of Low-Frequency Fluctuations (ALFF) and Fractional ALFF in Alzheimer Spectrum. Front Neurosci. 2018 Dec 20;12:975. doi: 10.3389/fnins.2018.00975.

35. Wang B, Li P, Li D, Niu Y, Yan T, Li T, Cao R, Yan P, Guo Y, Yang W, Ren Y, Li X, Wang F, Yan T*, Wu J, Zhang H, Xiang J. Increased Functional Brain Network Efficiency During Audiovisual Temporal Asynchrony Integration Task in Aging. Front Aging Neurosci. 2018 Oct 9;10:316. doi: 10.3389/fnagi.2018.00316..

36. Wang B, Miao L, Niu Y, Cao R, Li D, Yan P, Guo H, Yan T*, Wu J, Xiang J; Alzheimer’s Disease Neuroimaging Initiative. Abnormal Functional Brain Networks in Mild Cognitive Impairment and Alzheimer's Disease: A Minimum Spanning Tree Analysis. J Alzheimers Dis. 2018;65(4):1093-1107. doi: 10.3233/JAD-180603.

37. Zhang Z, Li C, Zhang J, Huang Q, Go R, Yan T* Wu J. Discrimination threshold for haptic volume perception of fingers and phalanges. Atten Percept Psychophys. 2018 Feb;80(2):576-585. doi: 10.3758/s13414-017-1453-z.

38. 裴广盈,闫天翼*,方伯言,吴景龙。 神经反馈技术在帕金森病治疗中的应用进展。 中国康复理论与实践 2018,24(12)

39. 裴广盈,王书杰,石忠焱,刘田田,仰若水,郭国鑫,吴景龙,闫天翼*. 基于失匹配负波的神经反馈技术在认知功能改善中的应用。中华神经医学杂志. 2020,(04)

国际/国家专利

1. 闫天翼、张鑫鑫、张津溥、石忠焱、孙思阳、仰若水、王丽   . 一种基于互联网的精神疾病评估与认知行为治疗系统, CN202110358901.8, 发明专利, 公开

1. 闫天翼、王凯、刘思宇、张德雨、陈端端、唐浩展、张弈诚、瑚耘慷、吴景龙. 基于动态SSVEP范式的脑机接口系统实现方法及装置, ZL202010877287.1, 发明专利 授权

2. 闫天翼、刘思宇、王凯、张德雨、陈端端、王欣、邵祎琦、徐自翀、倪传城、吴景龙. 一种人机融合脑控机器人系统, ZL202010878010.0, 发明专利, 授权

3. 闫天翼、刘思宇、张德雨、王凯、陈端端、王涵晓、范宇昂、康诺千、吴景龙. 一种阿尔兹海默病神经反馈康复系统, ZL202010877244.3, 发明专利, 授权

4. 闫天翼、杨彬彬、仰若水、王晨宇、石忠焱、吴景龙. 一种压电式触觉刺激装置, ZL202010154138.2, 发明专利, 授权

5. 吴景龙、王晨宇、闫天翼、仰若水、杨彬彬、石忠焱. 一种阵列式压电双晶片刺激系统, ZL202010154130.6, 发明专利,授权

6. 闫天翼、石忠焱、仰若水、刘田田、裴广盈、吴景龙. 一种便携式脑电采集系统, ZL201911283073.5, 发明专利, 授权

7. 闫天翼、石忠焱、陈端端、仰若水、吴景龙. 一种差频电干扰设备、系统及方法, ZL201911267110.3, 发明专利,授权

8. 吴景龙,闫天翼,王晨宇,仰若水,杨彬彬. 触觉刺激模块及多通道触觉刺激装置, ZL201910947398.2, 发明专利,授权

9. 闫天翼,张德雨,刘思宇,田振铎,陈端端,吴景龙. 一种物品标记方法、装置、设备和介质, ZL201910143449.6, 发明专利,授权

10. 韩璎,闫天翼,刘思宇,张德雨,赵明艳,陈端端,陈奕如,秦文硕,吴景龙. 一种脑电信号分类方法、装置、设备和介质, ZL201910033522.4, 发明专利, 授权

11. 陈端端,李旭辉,李振锋,闫天翼,许欢明,石悦. 主动脉夹层的模型建立方法、模型及模拟手术检测方法, ZL201910003999.8, 发明专利, 授权

12. 闫天翼,王璐瑶,贾世魁,陈端端,顾逸飞,赵子铭,吴景龙. 触觉刺激装置及触觉脑图谱测量系统, CN201811099299.5, 发明专利,公开

13. 闫天翼,陈端端,吴景龙,石忠焱,徐奥,陈奕如,王沁妍,钟允寒. 脑电帽伸缩式脑电采集干电极和系统, CN201811041863.8, 发明专利,公开

14. 陈卫衡;陈端端;何海军;李泰贤;王荣田;闫天翼. 股骨头图像分析方法、装置、服务器和介质, CN201810668292.4, 发明专利, 公开

15. 闫天翼,陈端端,高闯,吴景龙,谢觉如,刘云舟,毕泽伦,蒋铠阳,方宇辰. 基于体积的触觉检测设备, CN201811099300.4, 发明专利, 公开

16. 闫天翼,陈端端,沈亚奇,李章平,吴景龙. 差频电刺激设备、系统及方法, CN201810188822.5, 发明专利,公开

17. 陈端端,闫天翼,韦建雍,熊江,石悦,唐晓英. 虚拟支架在血管内扩张的模拟方法、装置及电子设备, CN201711292177.3, 发明专利 公开

18. 赵仑;马长书;闫天翼;王博;石国伟. 一种脑电信号的特征提取方法及装置 , ZL201710949210.9, 发明专利, 授权

19. 马长书;赵仑;王博;闫天翼;石国伟. 一种基于动物脑电识别的数据可视化处理方法及装置, ZL201710949198.1, 发明专利,  授权

20. 马长书;赵仑;王博;闫天翼;石国伟. 一种动物脑电分析系统, ZL201710948643.2, 发明专利,授权

21. 马长书;赵仑;王博;闫天翼;石国伟. 一种动物情绪脑电分析设备, ZL201710948805, 发明专利, 授权

22. 邓玉林;张德雨;张永谦;刘可夫;董一名;耿利娜;闫天翼. 一种用于核酸纯化,扩增及基因检测的系统及应用方法, ZL201710823869.X, 发明专利,授权

23. 马长书;赵仑;王博;闫天翼;石国伟. 一种动物脑电分类模型的构建方法及装置, CN201710949223.6, 发明专利, 公开

24. 陈端端,李振锋,许欢明,闫天翼,石悦,岳轶翔. 一种手术模拟设备及手术模拟系统, ZL201710897869.4, 发明专利, 授权

25. 闫天翼;马长书;赵仑;王博;石国伟. 一种前额区脑电分析方法, ZL201710949317.3, 发明专利, 授权

26. 马长书;赵仑;王博;闫天翼;石国伟. 一种判断动物心理状态的脑电分析装置及分析方法, CN201710949199.6, 发明专利, 公开

27. 闫天翼,裴广盈,李章平,沈亚奇,吴景龙,于净溪,周韵彤. 神经反馈装置、系统及方法, CN201710856790.7, 发明专利,公开

28. 张德雨;闫天翼;董一名;黄一恒;徐伟;董小楠. 一种基于机器人的开放式自动化导航方法及系统, CN201710556047.X, 发明专利,公开

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求才若渴

· 团队常年招收海内外在脑科学,穿戴式设备,医学图像处理、信号处理,机器学习等领域的有志之士

· 招收岗位:教授/研究员、副教授/副研究员、助理教授、博士后、博士生、硕士生

· 薪酬待遇:参考北京理工大学相应岗位聘用待遇薪酬

· 联系方式:手机/微信:15210108910;邮箱:yantianyi@bit.edu.cn